IPA: /vɪˈsɪsɪˌtjuːd/
KK: /vɪˈsɪsɪˌtud/
A change or variation, especially one that is unexpected or occurs by chance.
The vicissitudes of life can be challenging, but they also bring opportunities for growth.
Vicissitude is formed from "vicis" (meaning change or alternation) and the suffix "-tude" (indicating a state or condition). The word refers to the state of being subject to change or variation, often in a cyclical manner.
Think of 'change' ('vicis') to remember that 'vicissitude' means a state of change or variation.
No commonly confused words.