IPA: /ˌsʌb.stɪˈtjuː.ʃən/
KK: /sʌbstəˈtuːʃən/
The act of replacing one thing with another, or the thing that is used as a replacement.
The teacher made a substitution in the schedule to accommodate the guest speaker.
Substitution → It is formed from "sub-" (meaning under or below) and "stituere" (meaning to place or set). The word refers to placing something in the place of another, hence the act of substituting.
Think of placing something 'under' ('sub-') in the position of something else ('stituere') — that's why substitution means replacing one thing with another.