IPA: /rɪˈɡɑrdləs/
KK: /rɪˈɡɑrdləs/
Not paying attention to something; showing no concern or consideration for it.
She decided to go ahead with her plans regardless of the weather.
In spite of the circumstances or situations; without being affected by something.
She decided to go for a walk regardless of the rain.
Regardless → It is formed from "regard" (from Old French *regarder*, meaning to look at or consider) and "-less" (meaning without). The word "regardless" means without regard or consideration for something.
Think of 'looking at' ('regard') something and then 'not having' ('-less') any consideration for it — that's why regardless means not considering something.