IPA: /ˈproʊbænd/
KK: /ˈproʊbænd/
A person who has a specific condition or disorder and is the first one studied in research, especially in genetics.
The proband in the genetic study helped researchers understand the hereditary nature of the disease.
Proband is derived from the Latin root "probare" (meaning to test or prove) and the suffix "-and" (indicating a present participle). The word refers to something that is being tested or proven.
Think of 'proving' something ('probare') as you picture a test in progress — that's what proband means.