IPA: /ˈprɛərfəli/
KK: /ˈprɛərfəli/
In a way that shows devotion or earnestness in prayer.
She approached the situation prayerfully, seeking guidance and wisdom.
Prayerfully → It is formed from "prayer" (from Old French *preiere*, meaning a request or supplication) and "-fully" (meaning in a manner full of). The word "prayerfully" means in a manner full of prayer or with a spirit of prayer.
Think of being 'full of prayer' — 'prayer' refers to the act of supplication, and '-fully' indicates the manner in which something is done.