IPA: /ˈpɛrɪˌplæzəm/
KK: /pɛrɪˌplæzəm/
The area located between the plasma membrane and the outer membrane of certain bacteria, which contains enzymes and a layer of peptidoglycan.
In gram-negative bacteria, the periplasm plays a crucial role in nutrient processing and transport.
Periplasm is formed from "peri-" (meaning around) and "plasma" (from Greek "plasma", meaning something molded or formed). The term refers to the space around the plasma membrane of a cell, indicating an area that surrounds or is adjacent to the membrane.
Think of 'peri-' meaning 'around' and 'plasma' meaning 'formed substance' — this helps you remember that 'periplasm' refers to the area surrounding the cell's membrane.