Definition

The failure of paired chromosomes or sister chromatids to separate properly during cell division, which can lead to genetic disorders.

Example

Nondisjunction can result in conditions like Down syndrome, where an individual has an extra chromosome.

Conversation

Have you heard about nondisjunction in genetics?

Yeah, I think it has to do with chromosomes not separating properly, right?

Exactly! It can lead to some serious genetic disorders.

That's fascinating, I didn't realize how important that process is.

Synonyms & Antonyms

Root Explanation

Nondisjunction → It is formed from "non-" (meaning not) and "disjunction" (from Latin "disjunctio", meaning a separation or disconnection). The word describes a failure of chromosomes to separate properly during cell division, hence not achieving the expected separation.

Memory Tip

Think of 'not' ('non-') achieving a 'separation' ('disjunction') — that's why nondisjunction refers to the failure of chromosomes to separate.

Visually Confused Words