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missense

Upper-Intermediate (B2)

IPA: /ˈmɪsˌsɛns/

KK: /ˈmɪsˌsɛns/

adjective
Definition

Describing a type of genetic mutation that alters a codon, resulting in the substitution of one amino acid for another in a protein.


Example

The missense mutation in the gene caused a significant change in the protein's function.


Conversation
Sloth A
Have you heard about the latest findings on the missense mutations in genes?
Sloth B
Yeah, it's fascinating how they can impact protein synthesis.
Sloth A
I read that a single missense mutation can lead to significant changes in function.
Sloth B
Exactly! It really shows how delicate our genetic code is.

Synonyms & Antonyms
Synonyms
mutant
altered
changed
Antonyms
silent
neutral
unchanged
Root Explanation

Missense → It is formed from "mis-" (meaning wrong or incorrect) and "sense" (from Latin "sensum", meaning feeling or perception). The word "missense" refers to a type of mutation that results in the incorrect amino acid being incorporated into a protein, thus altering its function.

Memory Tip

Think of 'mis-' meaning wrong and 'sense' relating to perception or feeling — this helps you remember that missense refers to an incorrect perception in the context of genetic mutations.

Visually Confused Words
misenus
insense
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