IPA: /luːˈkoʊdɪstrəfi/
KK: /lʊˈkoʊdɪstrəfi/
A group of disorders that lead to the gradual breakdown of the white matter in the brain, caused by problems with the growth of the protective covering around nerve fibers.
Leukodystrophy can affect a person's ability to move and think clearly.
Leukodystrophy is formed from "leuko-" (from Greek "leukos", meaning white) and "dystrophy" (from Greek "dys-", meaning bad or difficult, and "trophe", meaning nourishment or growth). The term refers to a disorder characterized by the abnormal development or degeneration of the white matter in the brain, indicating a problem with the nourishment or growth of white matter.
Think of 'white' ('leuko-') and 'bad growth' ('dystrophy') to remember that leukodystrophy refers to a disorder affecting the white matter in the brain.