© 2026 Sloth Lingo. Learn easy. Lounge wisely.

leukodystrophy

Advanced (C1/C2)

IPA: /luːˈkoʊdɪstrəfi/

KK: /lʊˈkoʊdɪstrəfi/

noun
Definition

A group of disorders that lead to the gradual breakdown of the white matter in the brain, caused by problems with the growth of the protective covering around nerve fibers.


Example

Leukodystrophy can affect a person's ability to move and think clearly.


Conversation
Sloth A
Have you heard about leukodystrophy?
Sloth B
No, I haven't. What is it?
Sloth A
It's a condition that affects the white matter in the brain.
Sloth B
That sounds serious; I hope there are treatments available.

Synonyms & Antonyms
Synonyms
demyelination
disorder
condition
Antonyms
health
normalcy
stability
Root Explanation

Leukodystrophy is formed from "leuko-" (from Greek "leukos", meaning white) and "dystrophy" (from Greek "dys-", meaning bad or difficult, and "trophe", meaning nourishment or growth). The term refers to a disorder characterized by the abnormal development or degeneration of the white matter in the brain, indicating a problem with the nourishment or growth of white matter.

Memory Tip

Think of 'white' ('leuko-') and 'bad growth' ('dystrophy') to remember that leukodystrophy refers to a disorder affecting the white matter in the brain.

Visually Confused Words
lipodystrophy
hemodystrophy
Is this page helpful?