IPA: /ˌɪrɪˈmiːdiəbl/
KK: /ɪrɪˈmɛdiəbl/
Something that cannot be fixed or corrected; it is beyond repair or improvement.
The damage to the ancient artifact was deemed irremediable, leaving it forever altered.
Irremediable → It is formed from "in-" (meaning not) and "remediabilis" (from Latin "remedium", meaning remedy or cure, and "-abilis", meaning able to). The word describes a condition that cannot be remedied or cured.
Think of something that is 'not' ('in-') able to be 'cured' ('remediabilis') — that's why irremediable means it cannot be fixed.