IPA: //ˈfʊt.luːs//
KK: /ˈfʊtˌlus/
Not having any commitments or responsibilities, allowing someone to act freely and without restrictions.
After graduating, she felt footloose and ready to travel the world without any obligations.
Footloose is formed from "foot" (from Old English "fōt", meaning the lower limb) and "loose" (from Old English "losian", meaning to be free or unbound). The word describes someone who is free to move about without restrictions, particularly in a social or geographical sense.
Think of having your 'foot' free ('loose') to move wherever you want — that's what footloose means.
No commonly confused words.