IPA: /ˌɛksoʊˈnjuːkleɪs/
KK: /ɛksoʊˈnjuːkleɪs/
A type of enzyme that helps break down nucleic acids by removing single nucleotides from the ends of DNA or RNA chains.
Exonucleases play a crucial role in DNA repair and replication processes.
**Exonuclease** → It is formed from "exo-" (meaning outside) and "nuclease" (from "nucleus", meaning kernel or core, and "-ase", a suffix used for enzymes). The word refers to an enzyme that removes nucleotides from the ends of a nucleic acid chain, acting on the outside of the molecule.
Think of 'exo-' meaning 'outside' and 'nuclease' relating to the 'core' of nucleic acids — this helps you remember that an exonuclease works on the outside ends of nucleic acid chains.