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exonuclease

Upper-Intermediate (B2)

IPA: /ˌɛksoʊˈnjuːkleɪs/

KK: /ɛksoʊˈnjuːkleɪs/

noun
Definition

A type of enzyme that helps break down nucleic acids by removing single nucleotides from the ends of DNA or RNA chains.


Example

Exonucleases play a crucial role in DNA repair and replication processes.


Conversation
Sloth A
Have you heard about exonuclease enzymes and what they do?
Sloth B
Yeah, they remove nucleotides from the ends of DNA or RNA chains, right?
Sloth A
Exactly! It's fascinating how they play a role in DNA repair.
Sloth B
I know! It's amazing how every little enzyme has such an important function.

Synonyms & Antonyms
Synonyms
nuclease
enzyme
catalyst
Antonyms
Root Explanation

**Exonuclease** → It is formed from "exo-" (meaning outside) and "nuclease" (from "nucleus", meaning kernel or core, and "-ase", a suffix used for enzymes). The word refers to an enzyme that removes nucleotides from the ends of a nucleic acid chain, acting on the outside of the molecule.

Memory Tip

Think of 'exo-' meaning 'outside' and 'nuclease' relating to the 'core' of nucleic acids — this helps you remember that an exonuclease works on the outside ends of nucleic acid chains.

Visually Confused Words
nuclease
enucleate
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