IPA: /ˈdrʌɡləs/
KK: /drʌɡləs/
Not using any medications or substances that affect the body chemically.
The doctor recommended a drugless approach to managing pain through physical therapy and exercise.
Drugless → It is formed from "drug" (from Old French *drogue*, meaning a substance used for medicinal purposes) and "-less" (meaning without). The word "drugless" means without drugs or free from the use of drugs.
Think of being 'without' ('-less') any 'substance for medicine' ('drug') — that's what drugless means.