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demethylate

Upper-Intermediate (B2)

IPA: /dɪˈmɛθəˌleɪt/

KK: /dɛmɛθəˌleɪt/

verb
Definition

To remove one or more methyl groups from a chemical compound, particularly in biological contexts.


Example

Scientists are studying how to demethylate certain genes to understand their functions better.


Tense Forms

Past: demethylated

Past Participle: demethylated


Conversation
Sloth A
I was reading about how enzymes can demethylate DNA.
Sloth B
That's interesting! I didn't know they could do that.
Sloth A
Yeah, it plays a big role in regulating gene expression.
Sloth B
It really shows how complex biology can be!

Synonyms & Antonyms
Synonyms
dealkylate
demethylation
desmethylate
Antonyms
methylate
alkylate
add
Root Explanation

Demethylate → It is formed from "de-" (meaning removal or reversal) and "methyl" (from Greek "mēthylē", meaning a chemical group derived from methane) and "-ate" (a suffix used in chemistry to indicate a process). The word "demethylate" means to remove a methyl group from a molecule.

Memory Tip

Think of 'removing' ('de-') a 'methyl group' — that's why demethylate means to take away that specific chemical group.

Visually Confused Words
methylate
ethylate
deacetylate
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