IPA: /ˈkaʊntərˌsteɪn/
KK: /ˈkaʊntərˌsteɪn/
To apply a dye or stain to a specimen in order to enhance contrast and make certain features more visible under a microscope.
The scientist decided to counterstain the cells to better observe their structures.
Past: counterstained
Past Participle: counterstained
Counterstain → It is formed from "counter-" (meaning against) and "stain" (from Old French *esteindre*, meaning to extinguish or to dye). The word refers to a dye applied against the primary stain in microscopy or histology, providing contrast.
Think of applying a dye 'against' ('counter-') the primary color to create contrast — that's what counterstain means.