IPA: //ˈkoʊfæktər//
KK: /ˈkoʊˌfæktər/
A substance that is necessary for an enzyme to work properly, often a metal ion or a coenzyme, or a factor that helps another factor to produce a specific effect.
Zinc is an important cofactor for many enzymes in the body.
Cofactor → It is formed from "co-" (meaning together) and "facere" (meaning to do or make). The word refers to a substance that works together with another to facilitate a process, particularly in biological contexts.
Think of 'working together' ('co-') to 'make' something happen ('facere') — that's why a cofactor is something that helps in a process.