IPA: //ˈeɪ.poʊ.ɛn.zaɪm//
KK: /ˈæpoʊˌɛnzaɪm/
A type of protein that, when combined with a coenzyme, becomes part of an active enzyme that can catalyze reactions.
The apoenzyme needs a coenzyme to become active and perform its function in the cell.
Apoenzyme → It is formed from "apo-" (from Greek "apo", meaning away from or separate) and "enzyme" (from Greek "enzymon", meaning leaven or ferment). The word "apoenzyme" refers to the part of an enzyme that is inactive until it combines with a cofactor, thus being separate from its active form.
Think of 'apo-' meaning 'away from' and 'enzyme' as a fermenting agent — an apoenzyme is an enzyme that is inactive until it is combined with something else.