IPA: /əˈlɒstəri/
KK: /əˈlɒstəri/
A process in which the activity of a protein is changed by the binding of a molecule at a site other than the active site, leading to a change in its shape and function.
Allostery plays a crucial role in the regulation of enzyme activity.
Allostery → It is formed from "allo-" (from Greek "allos", meaning other) and "stereos" (meaning solid or three-dimensional). The term describes a process in biochemistry where the binding of a molecule at one site on a protein affects the function of the protein at a different site, hence the concept of 'other' ('allo-') affecting the 'solid' structure ('stereos').
Think of 'other' ('allo-') affecting the 'solid' structure ('stereos') of a protein, which helps you remember that allostery involves changes in protein function due to binding at a different site.