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allostery

Upper-Intermediate (B2)

IPA: /əˈlɒstəri/

KK: /əˈlɒstəri/

noun
Definition

A process in which the activity of a protein is changed by the binding of a molecule at a site other than the active site, leading to a change in its shape and function.


Example

Allostery plays a crucial role in the regulation of enzyme activity.


Conversation
Sloth A
Have you ever heard of allostery?
Sloth B
I think so, but I'm not entirely sure what it means.
Sloth A
It's really interesting; it refers to how a molecule can change shape and function.
Sloth B
Oh, that makes sense! I love learning about how things work at that level.

Synonyms & Antonyms
Synonyms
regulation
modulation
control
Antonyms
disorder
chaos
instability
Root Explanation

Allostery → It is formed from "allo-" (from Greek "allos", meaning other) and "stereos" (meaning solid or three-dimensional). The term describes a process in biochemistry where the binding of a molecule at one site on a protein affects the function of the protein at a different site, hence the concept of 'other' ('allo-') affecting the 'solid' structure ('stereos').

Memory Tip

Think of 'other' ('allo-') affecting the 'solid' structure ('stereos') of a protein, which helps you remember that allostery involves changes in protein function due to binding at a different site.

Visually Confused Words
balloter
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