Definition

Relating to a change in the shape and function of a protein, such as an enzyme, caused by the binding of a substance at a different site than the active one.

Example

The allosteric regulation of the enzyme allows for more precise control of metabolic pathways.

Conversation

Have you ever heard of allosteric regulation in enzymes?

Yeah, I think it has to do with how enzymes change shape, right?

Exactly! It’s fascinating how it can affect their activity without binding at the active site.

Totally! It shows how complex and interesting biochemistry can be.

Synonyms & Antonyms

Root Explanation

Allosteric → It is formed from "allo-" (from Greek "allos", meaning other) and "steric" (from Greek "stereos", meaning solid or three-dimensional). The term refers to the alteration of a protein's function due to the binding of a molecule at a site other than the active site, hence 'other solid' or 'other shape'.

Memory Tip

Think of 'allo-' meaning 'other' and 'steric' relating to 'shape' — this helps you remember that allosteric refers to changes in shape that affect function.

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