IPA: /əˈflɪkʃən/
KK: /əˈflɪkʃən/
A situation or condition that causes pain, suffering, or distress.
The illness was a great affliction to her family.
Affliction is formed from "ad-" (meaning to) and "fligere" (meaning to strike). The word describes a state of being struck or affected by something negative, such as pain or suffering.
Think of being 'struck' ('fligere') by something that causes you distress or pain, which helps you remember that 'affliction' refers to a state of suffering.